Predictions, Odds, and Betting Tips for the North London Derby: Tottenham vs. Arsenal in the Premier League

Both teams are facing challenges with their lineup. Arsenal is dealing with a midfield crisis as Declan Rice is suspended, and both Martin Odegaard and Mikel Merino are doubtful due to injuries.

Tottenham, meanwhile, could be without a few injured players, including midfielder Yves Bissouma.

BET NOW:Latest odds for Premier League games and best bets for the Tottenham vs. Arsenal match on BetMGM

It's an early test for both sides en route to their respective goals. Arsenal consider themselves title challengers, while Spurs will hope to push themselves towards a top-four finish.

MORE: A complete guide to betting on soccer in the United States

The Sporting News football betting expert Kyle Bonn shares his best bets, props, and high-risk/high-return fliers for some of the biggest matches in the sport each week. Since the start of 2024, he has correctly predicted 55% of match outcomes via the 3-way moneyline, for a profit of 56 units, correctly guessing the exact scoreline in 30 of 307 matches (10%).

Tottenham vs. Arsenal prediction, oddsMoneyline lean: Tottenham (+210)Score prediction: Tottenham 3-1 Arsenal

If there's ever a time to take the underdog in this famous derby, it's now. Arsenal will be playing on the road with a completely depleted midfield, which will allow Spurs to counter through the middle as Ange Postecoglou loves to do.

Arsenal under Mikel Arteta are reliant on their midfield, and even just missing Declan Rice could throw things out of whack. This will be the first time Arsenal will play without Rice in the lineup in a Premier League match since he joined, and their ability to play without him anchoring the midfield will be a test.

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(USA)Tottenham win+210Draw+270Arsenal win+115Both teams
to scoreY: -210
N: +140Over / Under
2.5 goalsO: -185
U: +130Arsenal
-0.5 goals+105Tottenham
+0.5 goals-150Tottenham vs. Arsenal match factsDate: Sunday, September 15, 2024Kickoff Time: 2 p.m. local (9 a.m. ET / 6 a.m. PT)Location: Tottenham Hotspur Stadium (London, England)Referee: Jarred Gillett, VAR: Stuart AtwellLast meeting: Tottenham 2-3 Arsenal (Apr. 28, 2024 | Premier League) Tottenham vs. Arsenal best betPick: First half over 1.5 goalsOdds: +135 (FanDuel)

These two teams love scoring early goals, especially against one another.

Incredibly, you have to go back five years to find a competitive matchup between these two clubs in which two or more goals were not scored in the first 45 minutes of the game, back to a 1-1 draw in March of 2019, a stretch of 10 straight matches.

This season, Tottenham and Arsenal have each scored a first-half goal in two of their three Premier League games.

Tottenham vs. Arsenal prop bet

Pick: Heung-Min Son to score or assist a goalOdds: +120 (FanDuel)

Tottenham haven't won many recent matches against Arsenal, but Heung-Min Son has played his part up front for Spurs.

The South Korea international has racked up 10 goal contributions in his last 10 meetings against Arsenal across all competitions, scoring or assisting a goal in seven of those matches.

He's also in good form, having already picked up a brace against Everton this season and racking up a goal and two assists against Oman in World Cup qualifying over the international break.